"Do you think the ayatollah is going to return to the table if Congress rejects this and arrange once more?" he told the Committee of Outside Relations research organization in New York.
Kerry has spent late days attempting to offer the hard-battled arrangement to incredulous Americans as the Republican-greater part, 535-part Place of Delegates has 60 days to audit the arrangement.
Congress can pass a movement of objection, which President Barack Obama can veto. An override of the veto obliges 66% support in both the House and Senate.
"Do you believe that they're going to stay there and other individuals on the planet are going to say, 'hey how about we run arrange with the United States, they have 535 secretaries of state'?," Kerry said.
"That is to say, please. I would be humiliated to attempt to go out. What am I going to say to individuals after this as secretary of state? 'Come arrange with us.' 'Goodness, Would you be able to convey?' Please."
Kerry cautioned that if Congress dismisses the arrangement, it could make Israel and the United States more secluded.
"Our companions in Israel could really end up being more disengaged and more faulted, and we would lose Europe and China and Russia regarding whatever military activity we may need to take in light of the fact that we will have walked out on an exceptionally honest to goodness program that permits us to put their project under serious scrutiny."
The secretary of state confronted rankling feedback on Thursday that he had been "fleeced" and "tricked" by Tehran, as he safeguarded the Iran atomic arrangement openly on Legislative center Slope.
He experienced a tidal wave of suspicion from Republicans on the Senate Outside Relations Advisory group, amid a marathon four-and-a-half-hour hearing.
The UN Security Committee consistently embraced the concession to Monday, making ready to the lifting of rebuffing financial authorizations.
The arrangement was come to in Vienna a week ago after intense transactions in the middle of Iran and the changeless Security Gathering individuals - England, China, France, Russia and the United States - in addition to Germany.